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Once you are done with network configuration, you need to run nmtui-connect to enable/disable network interface based on your need.

# nmtui-connect

Knowledge Base > Enable/disable network interface on CentOS 7 / CentOS 8 > image2020-2-27_11-0-41.png

In order to verify the network configuration settings, you can check the content of the interface file or you can issue the below commands.

# ifconfig ens3
# ip a
# ping -c2 google.com